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水通道蛋白4單克隆抗體
  • 產品貨號：
    BN41992M
  • 中文名稱：
    水通道蛋白4單克隆抗體
  • 英文名稱：
    Mouse anti-Aquaporin 4 Monoclonal antibody
  • 品牌：
    Biorigin

  • 貨號

    產品規(guī)格

    售價

    備注

  • BN41992M-50ul

    50ul

    ￥1486.00

    交叉反應：Human,Mouse,Rat 推薦應用：IHC-P,IHC-F,ICC,IF,ELISA

  • BN41992M-100ul

    100ul

    ￥2360.00

    交叉反應：Human,Mouse,Rat 推薦應用：IHC-P,IHC-F,ICC,IF,ELISA

產品描述

英文名稱Aquaporin 4
中文名稱水通道蛋白4單克隆抗體
別    名aquaporin 4; WCH4; Mercurial-insensitive water channel; MIWC; AQP 4; AQP4; Aquaporin4; HMIWC 2; HMIWC2; Mercurial insensitive water channel; MGC22454; MIWC; AQP4_HUMAN; Aquaporin-4; AQP-4.  
研究領域腫瘤  信號轉導  通道蛋白  新陳代謝  
抗體來源Mouse
克隆類型Monoclonal
克 隆 號6G1
交叉反應Human, Mouse, Rat, 
產品應用WB=1:500-1500 ELISA=1:1000-5000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量36kDa
細胞定位細胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原Recombinant human Aquaporin 4 Protein: 
亞    型IgG1
純化方法affinity purified by Protein G
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產品介紹This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.

Subunit:
Homotetramer. Part of a complex containing MLC1, TRPV4, HEPACAM and ATP1B1.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Brain, muscle, heart, kidney, lung, and trachea.

Similarity:
Belongs to the MIP/aquaporin (TC 1.A.8) family.

SWISS:
P55088

Gene ID:
361

Database links:

Entrez Gene: 281008 Cow

Entrez Gene: 361 Human

Entrez Gene: 11829 Mouse

Entrez Gene: 25293 Rat

Omim: 600308 Human

SwissProt: O77750 Cow

SwissProt: P55087 Human

SwissProt: P55088 Mouse

SwissProt: P47863 Rat

Unigene: 281008 Cow

Unigene: 315369 Human

Unigene: 250786 Mouse

Unigene: 90091 Rat



Important Note: