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尿苷二磷酸葡萄糖脫氫酶抗體
  • 產(chǎn)品貨號:
    BN41228R
  • 中文名稱:
    尿苷二磷酸葡萄糖脫氫酶抗體
  • 英文名稱:
    Rabbit anti-UGDH Polyclonal antibody
  • 品牌:
    Biorigin
  • 貨號

    產(chǎn)品規(guī)格

    售價

    備注

  • BN41228R-100ul

    100ul

    ¥2360.00

    交叉反應(yīng):Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應(yīng)用:WB,IHC-P,IHC-F,IF,ELISA

  • BN41228R-200ul

    200ul

    ¥3490.00

    交叉反應(yīng):Human,Mouse,Rat(predicted:Dog,Pig,Cow,Horse,Rabbit,Sheep) 推薦應(yīng)用:WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱UGDH
中文名稱尿苷二磷酸葡萄糖脫氫酶抗體
別    名UDP glucose dehydrogenase; GDH; UDP Glc dehydrogenasev UDP GlcDH; UDP glucose 6 dehydrogenase; UDP-Glc dehydrogenase; UDP-GlcDH; UDP-glucose 6-dehydrogenase; UDPGDH; UGD; Ugdh; UGDH_HUMAN; Uridine diphospho glucose dehydrogenase.  
研究領(lǐng)域細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(yīng)Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量55kDa
細(xì)胞定位細(xì)胞核 細(xì)胞漿 細(xì)胞外基質(zhì) 分泌型蛋白 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human UGDH/UDPGDH:421-494/494 
亞    型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010].

Function:
Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate.

Subunit:
Homohexamer.

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.

SWISS:
O60701

Gene ID:
7358

Database links:

Entrez Gene: 7358 Human

Entrez Gene: 22235 Mouse

Entrez Gene: 83472 Rat

Omim: 603370 Human

SwissProt: O60701 Human

SwissProt: O70475 Mouse

SwissProt: O70199 Rat

Unigene: 572518 Human

Unigene: 344831 Mouse

Unigene: 3967 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.












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