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14號(hào)染色體開(kāi)放閱讀框156抗體
  • 產(chǎn)品貨號(hào)：
    BN40655R
  • 中文名稱(chēng)：
    14號(hào)染色體開(kāi)放閱讀框156抗體
  • 英文名稱(chēng)：
    Rabbit anti-SLIRP/C14orf156 Polyclonal antibody
  • 品牌：
    Biorigin

  • 貨號(hào)

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  • BN40655R-100ul

    100ul

    ￥2360.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Pig,Rabbit) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

  • BN40655R-200ul

    200ul

    ￥3490.00

    交叉反應(yīng)：Human,Mouse(predicted:Rat,Pig,Rabbit) 推薦應(yīng)用：WB,IHC-P,IHC-F,IF,ELISA

產(chǎn)品描述

英文名稱(chēng)SLIRP/C14orf156
中文名稱(chēng)14號(hào)染色體開(kāi)放閱讀框156抗體
別    名C14orf156; Chromosome 14 open reading frame 156; DC50; DC23; PD04872; SLIRP; SRA stem loop interacting RNA binding protein, mitochondrial.  
研究領(lǐng)域細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  生長(zhǎng)因子和激素  結(jié)合蛋白  表觀遺傳學(xué)  
抗體來(lái)源Rabbit
克隆類(lèi)型Polyclonal
交叉反應(yīng)Human, Mouse,  (predicted: Rat, Pig, Rabbit, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量12kDa
細(xì)胞定位細(xì)胞核 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human SLIRP/C14orf156:31-100/109 
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Steroid receptor RNA activator (SRA, or SRA1; MIM 603819) is a complex RNA molecule containing multiple stable stem-loop structures that functions in coactivation of nuclear receptors. SLIRP interacts with stem-loop structure-7 of SRA (STR7) and modulates nuclear receptor transactivation (Hatchell et al., 2006 [PubMed 16762838]).[supplied by OMIM, Mar 2008]

Function:
RNA-binding protein that acts as a nuclear receptor corepressor. Probably acts by binding the SRA RNA, and repressing the SRA-mediated nuclear receptor coactivation. Binds the STR7 loop of SRA RNA. Also able to repress glucocorticoid (GR), androgen (AR), thyroid (TR) and VDR-mediated transactivation.

Subcellular Location:
Mitochondrial and Nuclear; Predominantly mitochondrial.

Tissue Specificity:
Ubiquitously expressed, with highest level in heart, liver, skeletal muscle and testis.

Similarity:
Contains 1 RRM (RNA recognition motif) domain.

SWISS:
Q9GZT3

Gene ID:
81892

Database links:

Entrez Gene: 81892 Human

Omim: 610211 Human

SwissProt: Q9GZT3 Human

Unigene: 655105 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.











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